BDBM50292467 Antioquine::Antioquine (S,R)::CHEMBL446564::CHEMBL452904

SMILES COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(c4)-c4cc(C[C@H]5N(C)CCc6cc(OC)c(Oc(c1O)c23)cc56)ccc4O

InChI Key InChIKey=MNNXIEANPHEHSB-WDYNHAJCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292467   

TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50292467(Antioquine | Antioquine (S,R) | CHEMBL446564 | CHE...)
Affinity DataIC50:  6.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50292467(Antioquine | Antioquine (S,R) | CHEMBL446564 | CHE...)
Affinity DataIC50:  3.18E+3nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50292467(Antioquine | Antioquine (S,R) | CHEMBL446564 | CHE...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in Wistar rat striatal membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50292467(Antioquine | Antioquine (S,R) | CHEMBL446564 | CHE...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed