BDBM50293967 (R)-5-Chloro-3-(4-methoxy-2,5-dimethylphenylamino)-1-(2-methoxy-1-methylethyl)pyrazin-2(1H)-one::CHEMBL550685
SMILES COC[C@@H](C)n1cc(Cl)nc(Nc2cc(C)c(OC)cc2C)c1=O
InChI Key InChIKey=QRGCYSHRQBEQSP-GFCCVEGCSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50293967
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 0.880nMAssay Description:Displacement of [125I]-o-CRF from CRFR1 in rat frontal cortex after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair