BDBM50296673 (E)-4,4-Dimethyl-1-quinolin-3-yl-pent-1-en-3-one::CHEMBL572128

SMILES CC(C)(C)C(=O)\C=C\c1cnc2ccccc2c1

InChI Key InChIKey=XROFVTPRFZVYMN-CMDGGOBGSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296673   

TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296673((E)-4,4-Dimethyl-1-quinolin-3-yl-pent-1-en-3-one |...)
Affinity DataKi:  5.23E+3nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296673((E)-4,4-Dimethyl-1-quinolin-3-yl-pent-1-en-3-one |...)
Affinity DataKi:  3.06E+4nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed