BDBM50300040 2-chloro-6,7-dimethoxy-N-(1-methylpiperidin-4-yl)quinazolin-4-amine::CHEMBL571951

SMILES COc1cc2nc(Cl)nc(NC3CCN(C)CC3)c2cc1OC

InChI Key InChIKey=GQUYPDZEIXUJLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300040   

TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300040(2-chloro-6,7-dimethoxy-N-(1-methylpiperidin-4-yl)q...)
Affinity DataIC50:  9.10E+6nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300040(2-chloro-6,7-dimethoxy-N-(1-methylpiperidin-4-yl)q...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed