BDBM50306428 2-{1'-[(adamantan-2-yl)carbamoyl]-7-chloro-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl}acetic acid::CHEMBL602248
SMILES OC(=O)CC1CC2(CCN(CC2)C(=O)NC2C3CC4CC(C3)CC2C4)c2c1cccc2Cl
InChI Key InChIKey=GTRLLSQFXNMEFO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50306428
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol by SPAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 11beta-HSD2More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10.7nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytes assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by SPAMore data for this Ligand-Target Pair