BDBM50313710 4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)biphenyl-2-carboxylic acid::CHEMBL1079517

SMILES CCCCc1cnc([nH]1)C(CCCO)Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=IZKNYADXWAWXCN-UHFFFAOYSA-N

Data  3 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50313710   

TargetBombesin receptor subtype-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Affinity DataIC50:  3.68E+3nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]bombesin from human BRS3 expressed in NFAT-CHO cells after 2 hrs by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonistic activity at human BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Affinity DataEC50:  174nMAssay Description:Agonistic activity at rat BRS3 expressed in HEK293AEO at 10 uM by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]bombesin from human bombesin BB1 receptor expressed in NFAT-CHO cells after 2 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]bombesin from human bombesin BB2 receptor expressed in NFAT-CHO cells after 2 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Affinity DataEC50:  238nMAssay Description:Agonistic activity at mouse BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed