BDBM50314083 (3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol-4-yl)methyl)-11-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-23-benzyl-35-(4-hydroxybenzyl)-14-((R)-1-hydroxyethyl)-32-isobutyl-28,31-dimethyl-1,9,12,15,18,21,24,27,30,33,36,37-dodecaoxotetracontahydro-1H-pyrrolo[1,2-z][1,4,7,10,13,16,19,22,26,29,35]undecaazacyclononatriacontine-3-carboxamide::CHEMBL1089951
SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)[C@@H](C)O
InChI Key InChIKey=GRUDSXXHTCXYAX-MOVTXUFESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50314083
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals
Curated by ChEMBL
Syntonix Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals
Curated by ChEMBL
Syntonix Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: 930nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals
Curated by ChEMBL
Syntonix Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: 140nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair