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Found 3 Enz. Inhib. hit(s) with Target = 'IgG receptor FcRn large subunit p51' and Ligand = 'BDBM50314083'
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314083((3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314083((3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol...)
Affinity DataKd:  930nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314083((3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol...)
Affinity DataKd:  140nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed