BDBM50316566 (+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4-fluorophenyl)-1H-indazol-5-yl)ethanol::1-(2,3-DICHLOROPHENYL)-2,2,2-TRIFLUORO-1-(1-(4-FLUOROPHENYL)-1H-INDAZOL-5-YL)ETHANOL (ENANTIOMERIC MIX)::1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4-fluorophenyl)-1H-indazol-5-yl)ethanol::CHEMBL1094208

SMILES OC(c1ccc2n(ncc2c1)-c1ccc(F)cc1)(c1cccc(Cl)c1Cl)C(F)(F)F

InChI Key InChIKey=SGKVPHOMCZNDPT-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50316566   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50316566((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...)
Affinity DataIC50:  87nMAssay Description:Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50316566((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...)
Affinity DataIC50:  87nMAssay Description:Binding affinity to human glucocorticoid receptor by fluorescence polariztion competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50316566((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50316566((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at glucocorticoid receptor in human MDA-kb2 cells transfected with MMTV-LUC assessed as induction of MMTV-LTR/promoter linked LUC ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50316566((+)-1-(2,3-dichlorophenyl)-2,2,2-trifluoro-1-(1-(4...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at glucocorticoid receptor in human fibroblast assessed as inhibition of IL-1-beta-induced IL6 production treated 1 hr before IL1-be...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed