BDBM50327046 1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea::1-{2-Fluoro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-oxy]phenyl}-3-[3-(trifluoromethyl)phenyl]urea::CHEMBL1254007::D3RKN_16

SMILES Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)c(F)c3)c12

InChI Key InChIKey=TWOLOZGQZKJZKJ-UHFFFAOYSA-N

Data  4 KI  24 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327046   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50327046(1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50327046(1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In DepthDetails PubMed