BDBM50327814 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea::CHEMBL1258670::US9296693, 36
SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F
InChI Key InChIKey=DPJZJKZKPMESQQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50327814
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis
Curated by ChEMBL
University Of California Davis
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 89.6nMAssay Description:Trans-diphenylpropene oxide is used in a radiometric competitive assay.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis
Curated by ChEMBL
University Of California Davis
Curated by ChEMBL
Affinity DataIC50: 0.700nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis
Curated by ChEMBL
University Of California Davis
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 6.5nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 9.30nMAssay Description:fluoresence competitive assay.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 6.5nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair