BDBM50327814 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea::CHEMBL1258670::US9296693, 36

SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=DPJZJKZKPMESQQ-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50327814   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis

Curated by ChEMBL
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California

US Patent
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  89.6nMAssay Description:Trans-diphenylpropene oxide is used in a radiometric competitive assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis

Curated by ChEMBL
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  0.700nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis

Curated by ChEMBL
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California

US Patent
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California

US Patent
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  9.30nMAssay Description:fluoresence competitive assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California

US Patent
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  6.5nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent