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Found 7 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50327814'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis

Curated by ChEMBL
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis

Curated by ChEMBL
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California Davis

Curated by ChEMBL
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  0.700nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  6.5nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  9.30nMAssay Description:fluoresence competitive assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50327814(1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Affinity DataIC50:  89.6nMAssay Description:Trans-diphenylpropene oxide is used in a radiometric competitive assay.More data for this Ligand-Target Pair
In DepthDetails US Patent