BDBM50331515 CHEMBL1708::PAROXETINE::Paroxetine hydrochloride::Paroxetine.HCl::Paxil::Paxil cr
SMILES Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1
InChI Key InChIKey=AHOUBRCZNHFOSL-YOEHRIQHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50331515
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of recombinant full-length human N-terminal GST tagged PKCalpha expressed in Baculovirus infected Sf9 insect cells using KRREILSRRPSYR as ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of bovine GRK5 assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of C-terminal hexahistidine tagged bovine GRK1 (535 residues) assessed as decrease in phosphorylation of tubulin preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of C-terminal hexahistidine tagged bovine GRK5 (561 residues) assessed as decrease in phosphorylation of tubulin preincubated for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of C-terminal hexahistidine tagged bovine GRK5 (561 residues) assessed as decrease in phosphorylation of light-activated bovine rod outer ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of C-terminal hexahistidine tagged bovine GRK1 (535 residues) assessed as decrease in phosphorylation of light-activated bovine rod outer ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+5nMAssay Description:Inhibition of bovine GRK1 (1 to 535 residues) assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair