BDBM50335711 CHEMBL1650355::N-2,6-bis4-methoxyphenyl)pyrimidin-4-yl)acetamide

SMILES COc1ccc(cc1)-c1cc(NC(C)=O)nc(n1)-c1ccc(OC)cc1

InChI Key InChIKey=VJDUMBCYXZCSRT-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50335711   

TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50335711(CHEMBL1650355 | N-2,6-bis4-methoxyphenyl)pyrimidin...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in human HeLa cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50335711(CHEMBL1650355 | N-2,6-bis4-methoxyphenyl)pyrimidin...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50335711(CHEMBL1650355 | N-2,6-bis4-methoxyphenyl)pyrimidin...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in human HeLa cell membranes after 180 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50335711(CHEMBL1650355 | N-2,6-bis4-methoxyphenyl)pyrimidin...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of CELT-228 from human adenosine A3 receptor expressed in human HeLa cells incubated for 30 mins by fluorescence polarization binding as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50335711(CHEMBL1650355 | N-2,6-bis4-methoxyphenyl)pyrimidin...)
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in human HeLa cells incubated for 30 mins by fluorescence polarization binding as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed