BDBM50342133 Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-imidazol-1-yl-propyl)-phenyl]-amine::CHEMBL517438::N-(4-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)phenyl)benzo[d]thiazol-2-amine::R-116010

SMILES C[C@H]([C@@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1)N(C)C

InChI Key InChIKey=WGVPSTQRQHGEEP-QRWLVFNGSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50342133   

TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  350nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CYP26 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  350nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342133(Benzothiazol-2-yl-[4-((1S,2S)-2-dimethylamino-1-im...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed