BDBM50342457 (S)-(2-(3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)(cyclobutyl)methanone::CHEMBL1771673
SMILES Clc1cccc(c1)-c1noc(n1)[C@@H]1CCCCN1C(=O)C1CCC1
InChI Key InChIKey=INTBVGDNRFKKFQ-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50342457
Affinity DataKi: 204nMAssay Description:Binding affinity to human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Negative allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+3nMAssay Description:Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium levelMore data for this Ligand-Target Pair