Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50342457'
Affinity DataKi: 204nMAssay Description:Binding affinity to human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Negative allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+3nMAssay Description:Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium levelMore data for this Ligand-Target Pair