BDBM50355501 INCB-018424::RUXOLITINIB::RUXOLITINIB PHOSPHATE::US10112907, Example 00016::US10766894, Compound TABLE 1.1::US10875847, Compound JAKAFI::US11203595, TABLE 1.1::US11279703, TABLE 6.147
SMILES N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
InChI Key InChIKey=HFNKQEVNSGCOJV-OAHLLOKOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50355501
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant JAK1 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant JAK2 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant JAK3 by TR-FRET assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant TYK2 by TR-FRET assayMore data for this Ligand-Target Pair