BDBM50357455 CHEMBL1917724

SMILES O=C1N2CCCC(=C2c2ccccc12)c1nc2ccncc2[nH]1

InChI Key InChIKey=OBSCRMJWHBYWSE-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357455   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL

LigandBDBM50357455(CHEMBL1917724)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDBPatents

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI