BDBM50363079 CHEMBL1944863::N-(4-bromophenyl)-3,4,5-trimethoxybenzamide (9)

SMILES COc1cc(cc(OC)c1OC)C(=O)Nc1ccc(Br)cc1

InChI Key InChIKey=IONWMMRVQGKQRL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50363079   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit?? Di Bari Aldo Moro

LigandPNGBDBM50363079(CHEMBL1944863 | N-(4-bromophenyl)-3,4,5-trimethoxy...)
Affinity DataIC50:  2.70E+4nMAssay Description:MDCK-MDR1 or MDCK-MRP1 cells (50,000 cells per well) were seeded into black CulturePlate (96-well plate) with 100 μL medium and allowed to becom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit?? Di Bari Aldo Moro

LigandPNGBDBM50363079(CHEMBL1944863 | N-(4-bromophenyl)-3,4,5-trimethoxy...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human MDR1 expressed in MDCK cells assessed as calcein AM accumulation after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50363079(CHEMBL1944863 | N-(4-bromophenyl)-3,4,5-trimethoxy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MRP1 expressed in MDCK cells assessed as calcein AM accumulation after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50363079(CHEMBL1944863 | N-(4-bromophenyl)-3,4,5-trimethoxy...)
Affinity DataIC50: >1.00E+5nMAssay Description:MDCK-MDR1 or MDCK-MRP1 cells (50,000 cells per well) were seeded into black CulturePlate (96-well plate) with 100 μL medium and allowed to becom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed