BDBM50365264 CHEMBL1738926

SMILES Cc1nnc2[C@H](NC(=O)OCc3ccccc3)N=C(c3ccccc3)c3ccccc3-n12

InChI Key InChIKey=TUWDLUFFAHHNEF-QHCPKHFHSA-N

Data  15 IC50  17 Kd

PDB links: 3 PDB IDs match this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50365264   

TargetBromodomain-containing protein 2(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataIC50:  29.9nMAssay Description:Displacement of acetylated histone peptide from BRD2-BD1,2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataIC50:  28.4nMAssay Description:Displacement of acetylated histone peptide from BRD3-BD1,2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataIC50:  15.5nMAssay Description:Displacement of acetylated histone peptide from BRD4-BD1,2 by FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataKd:  52nMAssay Description:Binding affinity to BRD2-BD1,2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataKd:  46nMAssay Description:Binding affinity to BRD3-BD1,2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataKd:  52.5nMAssay Description:Binding affinity to BRD4-BD1,2 by isothermal titration calorimetryMore data for this Ligand-Target Pair