BDBM50382493 CHEMBL2024116

SMILES Cc1cc(cc(C)n1)-c1nnc(N)nc1-c1ccc(F)cc1

InChI Key InChIKey=NEYZTILMBRSITP-UHFFFAOYSA-N

Data  7 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50382493   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataKi:  1.70nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293T cells by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataKi:  15.5nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataKi:  64nMAssay Description:Antagonist activity at human adenosine A2b receptor expressed in HEK293T cells by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataKi:  158nMAssay Description:Inhibition of adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataKi:  160nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in CHO cells by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in HEK293T cells by radioligand competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataIC50:  143nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in CHO-K1 cells assessed as reduction in cAMP level in presence of 10 uM adenosine by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataIC50:  0.790nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in CHO-K1 cells assessed as reduction in cAMP level in presence of 0.1 uM adenosine by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataIC50:  9.70nMAssay Description:Antagonist activity at rat adenosine 2A receptor assessed as reduction in cAMP level in presence of 0.1 uM adenosineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataIC50:  97nMAssay Description:Antagonist activity at rat adenosine 2A receptor assessed as reduction in cAMP level in presence of 10 uM adenosineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50382493(CHEMBL2024116)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at adenosine 2A receptor (unknown origin) in presence of 1 uM adenosineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed