BDBM50385590 CHEMBL2042829
SMILES CCN1c2ccc(Nc3ncc(Cl)c(N[C@@H]4[C@@H]5C[C@@H](C=C5)[C@@H]4C(N)=O)n3)c(OC)c2CCCC1=O
InChI Key InChIKey=GLGNXYJARSMNGJ-VKTIVEEGSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50385590
Affinity DataIC50: 45nMAssay Description:Inhibition of ALK tyrosine phosphorylation in human Karpas-299 cells after 2 hrs in presence of mouse plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human ALK cytoplasmic domain expressed in baculovirus using GST-PLCgamma as substrate preincubated for 15 mins before substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 597nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 225nMAssay Description:Inhibition of NPM-ALK autophosphorylation in human KARPAS299 cells in presence of mouse plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 597nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of NPM-ALK autophosphorylation in human KARPAS299 cellsMore data for this Ligand-Target Pair