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Found 6 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50385590'
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50385590(CHEMBL2042829)
Affinity DataIC50:  14nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50385590(CHEMBL2042829)
Affinity DataIC50:  14nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50385590(CHEMBL2042829)
Affinity DataIC50:  14nMAssay Description:Inhibition of human ALK cytoplasmic domain expressed in baculovirus using GST-PLCgamma as substrate preincubated for 15 mins before substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50385590(CHEMBL2042829)
Affinity DataIC50:  45nMAssay Description:Inhibition of NPM-ALK autophosphorylation in human KARPAS299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50385590(CHEMBL2042829)
Affinity DataIC50:  45nMAssay Description:Inhibition of ALK tyrosine phosphorylation in human Karpas-299 cells after 2 hrs in presence of mouse plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50385590(CHEMBL2042829)
Affinity DataIC50:  225nMAssay Description:Inhibition of NPM-ALK autophosphorylation in human KARPAS299 cells in presence of mouse plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed