BDBM50386424 CHEMBL2047528

SMILES CN(CCCOc1ccc2ccc(=O)oc2c1)Cc1cccc(OC(=O)NCCCCCc2ccccc2)c1

InChI Key InChIKey=LPCKLAOPKGFZKH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50386424   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  183nMpH: 9.0Assay Description:Inhibition of FAAH in rat brain membrane at pH 9 using N-arachidonoyl-[14C]-ethanolamine as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  4.10E+3nMpH: 7.4Assay Description:Inhibition of FAAH in rat brain membrane at pH 7.4 using N-arachidonoyl-[14C]-ethanolamine as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  50nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide preincubated for 20 mins before [14C]-anandamide addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  280nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  74.9nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 120 mins before substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  1.57nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of human recombinant FAAH in assessed as hydrolysis of [14C]-anandamide preincubated for 20 mins before [14C]-anandamide addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed