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Found 4 Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1 [30-579]' and Ligand = 'BDBM50386424'
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  50nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide preincubated for 20 mins before [14C]-anandamide addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  183nMpH: 9.0Assay Description:Inhibition of FAAH in rat brain membrane at pH 9 using N-arachidonoyl-[14C]-ethanolamine as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  280nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50386424(CHEMBL2047528)
Affinity DataIC50:  4.10E+3nMpH: 7.4Assay Description:Inhibition of FAAH in rat brain membrane at pH 7.4 using N-arachidonoyl-[14C]-ethanolamine as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed