BDBM50390700 CHEMBL2070227
SMILES O=C(N1CCC(C1)c1c[nH]c2ncccc12)C1(CC1)c1ccccc1
InChI Key InChIKey=KONDYSYBNMOPRN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50390700
Affinity DataIC50: 362nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cells assessed as conversion of cortisone to cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck Serono
Curated by ChEMBL
Merck Serono
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
Affinity DataIC50: 362nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cells assessed as conversion of cortisone to cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair