BDBM50390700 CHEMBL2070227

SMILES O=C(N1CCC(C1)c1c[nH]c2ncccc12)C1(CC1)c1ccccc1

InChI Key InChIKey=KONDYSYBNMOPRN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390700   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390700(CHEMBL2070227)
Affinity DataIC50:  362nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cells assessed as conversion of cortisone to cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390700(CHEMBL2070227)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390700(CHEMBL2070227)
Affinity DataIC50:  362nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cells assessed as conversion of cortisone to cortisol level after 150 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390700(CHEMBL2070227)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed