BDBM50394155 CHEMBL2158814
SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1
InChI Key InChIKey=QVLZVRFIGXNZMN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50394155
Affinity DataKi: 6.31nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:Displacement of [3H]pyrilamine from human H1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Antagonist activity at CCR3 assessed as inhibition of eotaxin bindingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of 3,7-Bis[2-(4-nitro[3,5-3H]phenyl)ethyl]-3,7-diazabicyclo[3.3.1]nonane from human ERG expressed in HEK cells after 3 hrs by TopCount a...More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Antagonist activity at CCR3 receptor in human poylmorphonuclear leukocytes assessed as inhibition of eotaxin-induced CD11b expression after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >1.58E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by electrophysiological ion flux assayMore data for this Ligand-Target Pair