BDBM50400312 CHEMBL2181330
SMILES C(CN1CCCC1)Oc1ccc2Nc3nccc(n3)-c3cccc(COCC=CCOCc1c2)c3
InChI Key InChIKey=HWXVIOGONBBTBY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50400312
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant JAK3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant JAK1 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as decrease in formation of 4-hydroxymephenytoin from mephenytoin substrate after 60 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant TYK2More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as decrease in formation of resorufin from ethoxyresorufin substrate after 5 mins by LC-MS/MSMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as decrease in formation of dextrorphan from dextromethorphan substrate after 30 mins by LC-M...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as decrease in formation of 1-hydroxymidazolam from midazolam substrate after 5 mins by LC-MS...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as decrease in formation of 4-hydroxytolbutamide from tolbutamide substrate after 60 mins by ...More data for this Ligand-Target Pair