BDBM50437067 CHEMBL2403550

SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2cc(F)ccc2C)c(C)c1

InChI Key InChIKey=RTNOWHVTNCEMDM-RXVVDRJESA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50437067   

TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cell membranes after 1 hr by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rat histamine H3 receptor transfected in CHO cell membranes after 1 hr by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50437067(CHEMBL2403550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed