BDBM50442702 CHEMBL2442511::US9296728, 26

SMILES OC(=O)c1cc2ccc(cc2oc1=O)N1CCCC1

InChI Key InChIKey=AZGXIHFVKOMJRL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50442702   

TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50442702(CHEMBL2442511 | US9296728, 26)
Affinity DataIC50:  220nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442702(CHEMBL2442511 | US9296728, 26)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50442702(CHEMBL2442511 | US9296728, 26)
Affinity DataIC50:  380nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed