BDBM50442702 CHEMBL2442511::US9296728, 26
SMILES OC(=O)c1cc2ccc(cc2oc1=O)N1CCCC1
InChI Key InChIKey=AZGXIHFVKOMJRL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50442702
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents of The University of Minnesota
US Patent
Regents of The University of Minnesota
US Patent
Affinity DataIC50: 220nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Institut De Recherche Exp£Rimentale Et Clinique (Irec)
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents of The University of Minnesota
US Patent
Regents of The University of Minnesota
US Patent
Affinity DataIC50: 380nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair