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Found 2 Enz. Inhib. hit(s) with Target = 'Monocarboxylate transporter 1' and Ligand = 'BDBM50442702'
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50442702(CHEMBL2442511 | US9296728, 26)
Affinity DataIC50:  220nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50442702(CHEMBL2442511 | US9296728, 26)
Affinity DataIC50:  380nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed