BDBM50446139 CHEMBL3108882::US10730870, Example 135::US11512083, Example 135
SMILES Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)on1
InChI Key InChIKey=FEFYMYQFVDBQAU-MJGOQNOKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50446139
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataKd: 1.50E+3nMAssay Description:Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+4nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataIC50: 1.92E+4nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair