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Found 2 Enz. Inhib. hit(s) with Target = 'von Hippel-Lindau disease tumor suppressor' and Ligand = 'BDBM50446139'
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50446139(CHEMBL3108882 | US10730870, Example 135 | US115120...)
Affinity DataIC50:  1.92E+4nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50446139(CHEMBL3108882 | US10730870, Example 135 | US115120...)
Affinity DataKd:  1.50E+3nMAssay Description:Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed