BDBM50449404 CHEMBL3127263

SMILES Oc1ccc(Br)cc1CN1C(N(Cc2cc(Br)ccc2O)c2cc(ccc12)[N+]([O-])=O)c1cc(Br)ccc1O

InChI Key InChIKey=DRJFKAQEUALKDH-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50449404   

TargetPresequence protease, mitochondrial(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50449404(CHEMBL3127263)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human PreP assessed as degradation of fluorogenic substrate V measured for 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50449404(CHEMBL3127263)
Affinity DataEC50:  402nMAssay Description:Agonist activity at human PreP assessed as degradation of biotin-labeled amyloid beta (1 to 42) after 2.5 hrs by Immunoblotting assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50449404(CHEMBL3127263)
Affinity DataEC50:  601nMAssay Description:Agonist activity at human PreP assessed as degradation of ATP synthase pF1beta subunit (2 to 56) after 2.5 hrs by Immunoblotting assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed