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Found 3 Enz. Inhib. hit(s) with Target = 'Presequence protease, mitochondrial' and Ligand = 'BDBM50449404'
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50449404(CHEMBL3127263)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human PreP assessed as degradation of fluorogenic substrate V measured for 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50449404(CHEMBL3127263)
Affinity DataEC50:  402nMAssay Description:Agonist activity at human PreP assessed as degradation of biotin-labeled amyloid beta (1 to 42) after 2.5 hrs by Immunoblotting assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50449404(CHEMBL3127263)
Affinity DataEC50:  601nMAssay Description:Agonist activity at human PreP assessed as degradation of ATP synthase pF1beta subunit (2 to 56) after 2.5 hrs by Immunoblotting assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed