BDBM50452630 CHEMBL4203412

SMILES C[n+]1cn([C@@H]2O[C@H](Cn3cc(nn3)P(O)([O-])=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12

InChI Key InChIKey=OXYNPFVALCVOEE-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50452630   

Target7-methylguanosine phosphate-specific 5'-nucleotidase(Human)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50452630(CHEMBL4203412)
Affinity DataIC50: 8.78E+4nMAssay Description:Inhibition of recombinant His6/SUMO-tagged human cN3B (1 to 300 residues) expressed in Escherichia coli BL21(DE3) RIL assessed as reduction in dephos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Targetm7GpppX diphosphatase(Human)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50452630(CHEMBL4203412)
Affinity DataIC50: 2.44E+5nMAssay Description:Inhibition of human DCPS using m7GMPF as substrate after 30 mins by nucleoside 5'-fluorophosphate probe based HTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
Target7-methylguanosine phosphate-specific 5'-nucleotidase(Human)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50452630(CHEMBL4203412)
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of recombinant His6/SUMO-tagged human cN3B (1 to 300 residues) expressed in Escherichia coli BL21(DE3) RIL assessed as reduction in dephos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50452630(CHEMBL4203412)
Affinity DataKd:  5.90E+3nMAssay Description:Inhibition of fluorescein-labeled m7GDPC4H5 binding to mouse eIF4E (28 to 217 residues) by MST methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50452630(CHEMBL4203412)
Affinity DataKi:  3.82E+5nMAssay Description:Inhibition of eIF4E (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed