BDBM50453681 CHEMBL4204445

SMILES COc1ccc(\C=C2/NC(=S)N(C2=O)c2ccccc2)cc1OC

InChI Key InChIKey=YCHBBPYKSIETDT-UVTDQMKNSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50453681   

TargetProteasome subunit beta type-5(Homo sapiens (Human))TBA
LigandPNGBDBM50453681(CHEMBL4204445)
Affinity DataKi:  2.01E+3nMAssay Description:Inhibition of 20s immunoproteasome beta5 chymotrypsin-like activity in human spleen using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 10 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50453681(CHEMBL4204445)
Affinity DataKi:  2.64E+3nMAssay Description:Inhibition of 20s immunoproteasome beta1 caspase-like activity in human spleen using Ac-Pro-Ala-Leu-AMC as substrate after 10 mins by fluorescence as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))TBA
LigandPNGBDBM50453681(CHEMBL4204445)
Affinity DataKi:  1.36E+4nMAssay Description:Inhibition of 20s constitutive proteasome beta5 chymotrypsin-like activity in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed