BDBM50453799 Niguldipine
SMILES COC(=O)C1=C(C)NC(C)=C([C@H]1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1
InChI Key InChIKey=SVJMLYUFVDMUHP-XIFFEERXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50453799
Affinity DataKi: 0.380nMAssay Description:Binding affinity of the compound towards Alpha-1A adrenergic receptor in bovine brainusing [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Binding affinity of the compound towards Alpha-1A adrenergic receptor in rat hipocampal membranes using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity of the compound towards Alpha-1B adrenergic receptor hamster smooth muscle using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Binding affinity of the compound towards Alpha-1D adrenergic receptor in rat brain using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:Binding affinity of the compound towards Dopamine receptor D2 in rat striatum using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Binding affinity of the compound towards Alpha-1B adrenergic receptor in rat liver using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound towards 5-hydroxytryptamine 1A receptor in rat hypocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair