BDBM50459892 CHEMBL4228824

SMILES CNC(=O)c1ncn-2c1[C@@H](C)N=C(c1ccccc1F)c1cc(ccc-21)C#C

InChI Key InChIKey=PIPOCLOMPZRSLC-CYBMUJFWSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50459892   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50459892(CHEMBL4228824)
Affinity DataKi:  55nMAssay Description:Binding affinity to GABA-A alpha5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50459892(CHEMBL4228824)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]-flunitrazepam from recombinant rat GABAA receptor alpha5beta3gamma2S expressed in HEK293 cell membranes after 90 mins by liquid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-3/gamma-2(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50459892(CHEMBL4228824)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]-flunitrazepam from recombinant rat GABAA receptor alpha2beta3gamma2S expressed in HEK293 cell membranes after 90 mins by liquid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50459892(CHEMBL4228824)
Affinity DataKi:  360nMAssay Description:Binding affinity to GABA-A alpha2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50459892(CHEMBL4228824)
Affinity DataKi:  660nMAssay Description:Binding affinity to GABA-A alpha3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50459892(CHEMBL4228824)
Affinity DataKi:  660nMAssay Description:Displacement of [3H]-flunitrazepam from recombinant rat GABAA receptor alpha3beta3gamma2S expressed in HEK293 cell membranes after 90 mins by liquid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50459892(CHEMBL4228824)
Affinity DataKi:  850nMAssay Description:Displacement of [3H]-flunitrazepam from recombinant rat GABAA receptor alpha1beta3gamma2S expressed in HEK293 cell membranes after 90 mins by liquid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50459892(CHEMBL4228824)
Affinity DataKi:  850nMAssay Description:Binding affinity to GABA-A alpha1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed