BDBM50463040 CHEMBL4247590

SMILES OC(=O)c1cc(ccc1O)-c1ccc(C=O)o1

InChI Key InChIKey=CYEKBFDCMORSFM-UHFFFAOYSA-N

Data  5 KI  5 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50463040   

TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  1.40E+3nMAssay Description:Non-competitive inhibition of human recombinant LDHA assessed as inhibition constant using varying concentration of pyruvate as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  7.90E+3nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged mouse recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  1.29E+4nMAssay Description:Non-competitive inhibition of human recombinant LDHB assessed as inhibition constant using varying concentration of pyruvate as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  1.82E+4nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  4.72E+4nMAssay Description:Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli using glycolate as substrate by Dixon plot and Cornish-Bowden plot an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human recombinant LDHA using pyruvate as substrate preincubated for 10 mins followed by substrate addition and measured every 60 sec fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human recombinant LDHB using pyruvate as substrate preincubated for 10 mins followed by substrate addition and measured every 60 sec fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataIC50:  2.82E+4nMAssay Description:Inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells using glycolate as substrate p...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataEC50:  1.12E+4nMAssay Description:Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataEC50:  3.45E+3nMAssay Description:Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataIC50:  3.82E+4nMAssay Description:Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli using glycolate as substrate by sulfonated DCIP dye-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataEC50:  8.36E+3nMAssay Description:Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of N-terminal His-tagged mouse recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells using glycolate as substrate p...More data for this Ligand-Target Pair
In DepthDetails PubMed