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Found 9 Enz. Inhib. hit(s) with Target = '2-Hydroxyacid oxidase 1' and Ligand = 'BDBM50463040'
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  7.90E+3nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged mouse recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  1.82E+4nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  4.72E+4nMAssay Description:Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli using glycolate as substrate by Dixon plot and Cornish-Bowden plot an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of N-terminal His-tagged mouse recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells using glycolate as substrate p...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataIC50:  2.82E+4nMAssay Description:Inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells using glycolate as substrate p...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataIC50:  3.82E+4nMAssay Description:Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli using glycolate as substrate by sulfonated DCIP dye-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataEC50:  3.45E+3nMAssay Description:Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataEC50:  8.36E+3nMAssay Description:Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataEC50:  1.12E+4nMAssay Description:Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed