BDBM50463980 CHEMBL4246881
SMILES COc1ccccc1N1CCN(Cc2ccc(OCc3cn(CCCCCCCCN(C)CCCCCNC(=O)COc4cncc(c4)C#Cc4csc(C)n4)nn3)c(OC)c2)CC1
InChI Key InChIKey=CQZPSNRJVCQSPU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50463980
Affinity DataKi: 45nMAssay Description:Displacement of [3H]-Raclopride from recombinant human dopamine D2 receptor expressed in HEK293T cell membranes co-expressing mGluR5a (unknown origin...More data for this Ligand-Target Pair
Affinity DataKi: 132nMAssay Description:Displacement of [3H]-Raclopride from recombinant human dopamine D2 receptor expressed in HEK293T cell membranes after 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [3H]MPEP from recombinant mGluR5 (unknown origin) expressed in HEK293T cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Displacement of [3H]MPEP from recombinant mGluR5a (unknown origin) expressed in HEK293T cell membranes co-expressing human dopamine D2 receptor after...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Homo sapiens (Human))
Ghent University
Curated by ChEMBL
Ghent University
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK p...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Antagonist activity at mGluR5 (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK phosphorylation preincubated f...More data for this Ligand-Target Pair