BDBM50465645 CHEMBL4288478

SMILES CN[C@@H](C)C(=O)N[C@@H](Cc1cc(C)c(cc1F)C(F)(F)F)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c1cccc2F

InChI Key InChIKey=NTTJUNKJFQKLSG-RGWZMNCVSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465645   

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of California Riverside

Curated by ChEMBL
LigandPNGBDBM50465645(CHEMBL4288478)
Affinity DataKd:  86nMAssay Description:Binding affinity to N-terminal His-tagged human recombinant XIAP BIR3 (253 to 347 residues) expressed in Escherichia coli BL21(DE3) Gold by isotherma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
University Of California Riverside

Curated by ChEMBL
LigandPNGBDBM50465645(CHEMBL4288478)
Affinity DataIC50:  4.5nMAssay Description:Displacement of AVPIAQKSEK-biotin from cIAP1 BIR3 (unknown origin) after 1 hr by DELFIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
University Of California Riverside

Curated by ChEMBL
LigandPNGBDBM50465645(CHEMBL4288478)
Affinity DataIC50:  15nMAssay Description:Displacement of AVPIAQKSEK-biotin from cIAP2 BIR3 (unknown origin) after 1 hr by DELFIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of California Riverside

Curated by ChEMBL
LigandPNGBDBM50465645(CHEMBL4288478)
Affinity DataIC50:  37nMAssay Description:Displacement of AVPIAQKSEK-biotin from N-terminal His-tagged human recombinant XIAP BIR3 (253 to 347 residues) expressed in Escherichia coli BL21(DE3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed