BDBM50466605 CHEMBL4276776

SMILES [I-].COc1cc(OC)cc(\C=C\c2ccc(OCCCC[P+](c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c1

InChI Key InChIKey=XRWZTUPDNNSGAE-QZQOTICOSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466605   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466605(CHEMBL4276776)
Affinity DataKi:  1.83E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from human alpha7 nAChR expressed in human SH-SY5Y cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466605(CHEMBL4276776)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50466605(CHEMBL4276776)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mins at -...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed