BDBM50469125 CHEMBL1210959

SMILES [#6]-[#8]-c1ccc(\[#6]=[#6]-2/c3cccc(Cl)c3-[#6](=O)-c3c(Cl)cccc-23)c(-[#8]-[#6])c1-[#8]

InChI Key InChIKey=DASNMAIRNLIRCK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469125   

TargetAndrogen receptor(Homo sapiens (Human))
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469125(CHEMBL1210959)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM50469125(CHEMBL1210959)
Affinity DataIC50:  360nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469125(CHEMBL1210959)
Affinity DataIC50:  170nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469125(CHEMBL1210959)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed