BDBM50483022 8-Methoxy Fluoroquinolone::CHEMBL1276635
SMILES CC[C@@H]1CCN(C1)c1c(F)cc2c(c1OC)n(cc(C(O)=O)c2=O)C1CC1
InChI Key InChIKey=FGBGEKHVEJJJLT-LLVKDONJSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50483022
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
University Of Minnesota Medical School
Curated by ChEMBL
University Of Minnesota Medical School
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of DNA supercoiling activity of Escherichia coli DNA gyrase gyrA A67S mutantMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University Of Minnesota Medical School
Curated by ChEMBL
University Of Minnesota Medical School
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of DNA supercoiling activity of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
University Of Minnesota Medical School
Curated by ChEMBL
University Of Minnesota Medical School
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of DNA supercoiling activity of Escherichia coli DNA gyrase gyrA G81C mutantMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
University Of Minnesota Medical School
Curated by ChEMBL
University Of Minnesota Medical School
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of DNA supercoiling activity of Escherichia coli DNA gyrase gyrA S83W mutantMore data for this Ligand-Target Pair