BDBM50483144 CHEMBL1630057::GSK2210875

SMILES C[C@@H](OC(=O)Nc1ccccc1)c1sc2ncnn2c1C

InChI Key InChIKey=AOUUMBPBMVOBSP-SNVBAGLBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50483144   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(CHEMBL1630057 | GSK2210875)
Affinity DataIC50:  3.16E+4nMAssay Description:Antagonist activity at mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(CHEMBL1630057 | GSK2210875)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at mGluR5 in mouse astrocytes assessed as inhibition of L-quisqualate induced calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(CHEMBL1630057 | GSK2210875)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed