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Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50483144'
TargetMetabotropic glutamate receptor 5(Mus musculus)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(CHEMBL1630057 | GSK2210875)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at mGluR5 in mouse astrocytes assessed as inhibition of L-quisqualate induced calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(CHEMBL1630057 | GSK2210875)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(CHEMBL1630057 | GSK2210875)
Affinity DataIC50:  3.16E+4nMAssay Description:Antagonist activity at mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed