BDBM50487259 CHEBI:64219::[3H]NEMONAPRIDE

SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@@H]1CCN(Cc2ccccc2)[C@@H]1C

InChI Key InChIKey=KRVOJOCLBAAKSJ-RDTXWAMCSA-N

Data  6 KI  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50487259   

TargetD(4) dopamine receptor(Homo sapiens (Human))
City University Of New York

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]-methylspiperone from dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
City University Of New York

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]-methylspiperone from dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
City University Of New York

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]-N-Methylspiperone from human dopamine D4 receptor expressed in stable HEK cells incubated for 90 mins by microbeta counting meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
City University Of New York

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-N-Methylspiperone from dopamine D3 receptor (unknown origin) incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
City University Of New York

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]N-methylspiperone from dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
City University Of New York

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]DTG from sigma2 receptor(unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))TBA
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKd:  0.0160nMAssay Description:Binding affinity to Rattus norvegicus (rat) chimeric dopamine D2 trunk/D2 tail receptor transfected in african green monkey COS7 cells after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKd:  0.0640nMAssay Description:Binding affinity to Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr by beta scintill...More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Rattus norvegicus (rat))TBA
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKd:  0.0140nMAssay Description:Binding affinity to Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr by beta scintill...More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKd:  0.0600nMAssay Description:Binding affinity to Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cells after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails Article